If you'd meet morpheus would you pick the blue or the red pill?
I wouldn't care. The matrix is just as meaningful as the real world because, in truth, nothing is real. There is only an illusion of reality, one that you can only break free from once you perish. The real world might not be real, but neither is the matrix. It's all a giant illusion, making us think that certain things have more meaning than others.
You punch the illusion, it punches back. It's easier to live a peaceful life than to live one where your actions ultimately won't make a difference, even though you fight like hell to make it so. Cherish the illusion.